Neosolue-AquaS is “ Water-soluble ester oil ”. It can be compatible with any ratio of water, and can be formulated in water-based formulation such as lotions transparently. It is water-soluble, but it also has oil-like properties. It has excellent transepidermal water loss (TEWL) reducing effect, improving effect of skin barrier function, and moisture retention effect. It provides moistness without sticky feeling, and reduces the stickiness of glycerin or oils.